I realize that there has probably been a thread about this in the past but I couldn't find a recent one and don't feel like necroing an old one.
Unarmed combat is extremely powerful, too powerful compared to other weapons. you can kill someone with unarmed combat before they can even get 2 swings off with their weapon.
Recently I've found myself having an axe in my right hand for logging and leaving my left empty so I can spam punch at anything that comes around. The punch swing is almost instant so it's nearly impossible to miss and it does at least as much damage as a weapon attack.