After I minimize Xsyon, then reopen the window, suddenly it's like it wont accept any input from my mouse OR keyboard afterwards. The game still runs, I just can get any input to go through. So I have to restart the game. This does not happen if I run the game in window mode.
I noticed running the game started the patcher and then the game exe so maybe you need to go into property's of the game exe and have it run as admin always