I would support banning macro users and auto-log-off people who are afk for a certain amount of time. The former because it would destroy the game. The latter because it can be used beneficially for all rather than a select group, while reducing load on the servers. It could also benefit everyone because if you forget you had the game on, your out in the wilderness -- no sense getting killed and stripped because you went out to lunch and forgot you had Xsyon open.
However, adding a que to the game would be slightly detrimental to overall progress. Rather than incorperating a fix like that, I would rather a more permanent solution be found, such as increasing the max stable amount of players on at any given time.
I'm sorry to admit this to you look at the history of sandbox games with skill gains like those of Xsyon. Ultima Online and Darkfall are huge examples. Whenever you have a game with freedom like this some asshole will come along and macro it up and there is nothing an independent developer like this will be able to do about it.